Combined burden and functional impact tests for cancer driver discovery using DriverPower

The discovery of driver mutations is one of the key motivations for cancer genome sequencing. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we describe DriverPower, a sof...

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Detalles Bibliográficos
Autores principales: Shuai, Shimin, Gallinger, Steven, Stein, Lincoln D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002750/
https://www.ncbi.nlm.nih.gov/pubmed/32024818
http://dx.doi.org/10.1038/s41467-019-13929-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002750/
https://www.ncbi.nlm.nih.gov/pubmed/32024818
http://dx.doi.org/10.1038/s41467-019-13929-1

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