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MiR-502 is the first reported miRNA simultaneously targeting two components of the classical non-homologous end joining (C-NHEJ) in pancreatic cell lines

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Acquired inherited and/or somatic mutations drive its development. In order to prevent the formation of these mutations, precise and immediate repair of any DNA damage is indispensable. Non-homologous end-joining (NHEJ) is the...

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Detalles Bibliográficos
Autores principales: Smolinska, Agnieszka, Swoboda, Julia, Fendler, Wojciech, Lerch, Markus M., Sendler, Matthias, Moskwa, Patryk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002776/
https://www.ncbi.nlm.nih.gov/pubmed/32042960
http://dx.doi.org/10.1016/j.heliyon.2020.e03187