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MiR-502 is the first reported miRNA simultaneously targeting two components of the classical non-homologous end joining (C-NHEJ) in pancreatic cell lines
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Acquired inherited and/or somatic mutations drive its development. In order to prevent the formation of these mutations, precise and immediate repair of any DNA damage is indispensable. Non-homologous end-joining (NHEJ) is the...
Autores principales: | Smolinska, Agnieszka, Swoboda, Julia, Fendler, Wojciech, Lerch, Markus M., Sendler, Matthias, Moskwa, Patryk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002776/ https://www.ncbi.nlm.nih.gov/pubmed/32042960 http://dx.doi.org/10.1016/j.heliyon.2020.e03187 |
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