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Genomic diversity affects the accuracy of bacterial single-nucleotide polymorphism–calling pipelines

BACKGROUND: Accurately identifying single-nucleotide polymorphisms (SNPs) from bacterial sequencing data is an essential requirement for using genomics to track transmission and predict important phenotypes such as antimicrobial resistance. However, most previous performance evaluations of SNP calli...

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Detalles Bibliográficos
Autores principales: Bush, Stephen J, Foster, Dona, Eyre, David W, Clark, Emily L, De Maio, Nicola, Shaw, Liam P, Stoesser, Nicole, Peto, Tim E A, Crook, Derrick W, Walker, A Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002876/
https://www.ncbi.nlm.nih.gov/pubmed/32025702
http://dx.doi.org/10.1093/gigascience/giaa007