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Icariin promotes osteogenic differentiation of BMSCs by upregulating BMAL1 expression via BMP signaling

Increasing research has demonstrated that expression of brain and muscle ARNT-like 1 (BMAL1) and other circadian clock genes can be regulated by drugs and toxicants. We previously demonstrated that icariin, extracted from Herba Epimedii, sromotes osteogenic differentiation. However, the mechanism un...

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Detalles Bibliográficos
Autores principales: Huang, Zengfa, Wei, Hui, Wang, Xiang, Xiao, Jianwei, Li, Zuoqin, Xie, Yuanliang, Hu, Yun, Li, Xiang, Wang, Zheng, Zhang, Shutong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002972/
https://www.ncbi.nlm.nih.gov/pubmed/32016461
http://dx.doi.org/10.3892/mmr.2020.10954