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ROS/p53/miR-335-5p/Sp1 axis modulates the migration and epithelial to mesenchymal transition of JEG-3 cells

Differential expression of microRNA (miR)-335-5p, a key tumor suppressor, has been detected in pre-eclampsia (PE) placentas. However, the role of miR-335-5p in the pathogenesis of PE and the factor modulating its aberrant expression remain unknown. The present study used JEG-3 cells in vitro to inve...

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Detalles Bibliográficos
Autores principales: Lu, Wei, Ma, Yu-Yan, Shao, Qian-Qian, Liang, Jie, Qi, Tong-Tong, Huang, Yi, Wang, Qing-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003020/
https://www.ncbi.nlm.nih.gov/pubmed/31894323
http://dx.doi.org/10.3892/mmr.2019.10901