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General mechanism of JQ1 in inhibiting various types of cancer

Bromodomain-containing 4 (BRD4) is a histone modification reader and transcriptional regulator that has been reported to interact with acetylated lysine histone motifs transcription factors (TFs), transcription co-activators and RNA polymerase II. The selective small molecule inhibitor JQ1, which bi...

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Detalles Bibliográficos
Autores principales: Jiang, Guojuan, Deng, Wanglong, Liu, Yang, Wang, Chengde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003028/
https://www.ncbi.nlm.nih.gov/pubmed/31922235
http://dx.doi.org/10.3892/mmr.2020.10927