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General mechanism of JQ1 in inhibiting various types of cancer
Bromodomain-containing 4 (BRD4) is a histone modification reader and transcriptional regulator that has been reported to interact with acetylated lysine histone motifs transcription factors (TFs), transcription co-activators and RNA polymerase II. The selective small molecule inhibitor JQ1, which bi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003028/ https://www.ncbi.nlm.nih.gov/pubmed/31922235 http://dx.doi.org/10.3892/mmr.2020.10927 |