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Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes

Homing based gene drives (HGD) possess the potential to spread linked cargo genes into natural populations and are poised to revolutionize population control of animals. Given that host encoded genes have been identified that are important for pathogen transmission, targeting these genes using guide...

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Detalles Bibliográficos
Autores principales: Kandul, Nikolay P., Liu, Junru, Buchman, Anna, Gantz, Valentino M., Bier, Ethan, Akbari, Omar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003086/
https://www.ncbi.nlm.nih.gov/pubmed/31882406
http://dx.doi.org/10.1534/g3.119.400985