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Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes
Homing based gene drives (HGD) possess the potential to spread linked cargo genes into natural populations and are poised to revolutionize population control of animals. Given that host encoded genes have been identified that are important for pathogen transmission, targeting these genes using guide...
Autores principales: | Kandul, Nikolay P., Liu, Junru, Buchman, Anna, Gantz, Valentino M., Bier, Ethan, Akbari, Omar S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003086/ https://www.ncbi.nlm.nih.gov/pubmed/31882406 http://dx.doi.org/10.1534/g3.119.400985 |
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