Blinded In Silico Drug Trial Reveals the Minimum Set of Ion Channels for Torsades de Pointes Risk Assessment

Torsades de Pointes (TdP) is a type of ventricular arrhythmia which could be observed as an unwanted drug-induced cardiac side effect, and it is associated with repolarization abnormalities in single cells. The pharmacological evaluations of TdP risk in previous years mainly focused on the hERG chan...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Qu, Yusheng, Passini, Elisa, Bueno-Orovio, Alfonso, Liu, Yang, Vargas, Hugo M., Rodriguez, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003137/
https://www.ncbi.nlm.nih.gov/pubmed/32082155
http://dx.doi.org/10.3389/fphar.2019.01643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003137/
https://www.ncbi.nlm.nih.gov/pubmed/32082155
http://dx.doi.org/10.3389/fphar.2019.01643

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