Discovery of Lonafarnib-Like Compounds: Pharmacophore Modeling and Molecular Dynamics Studies

[Image: see text] Progeria is a globally noticed rare genetic disorder manifested by premature aging with no effective treatment. Under these circumstances, farnesyltransferase inhibitors (FTIs) are marked as promising drug candidates. Correspondingly, a pharmacophore model was generated exploiting...

Descripción completa

Detalles Bibliográficos
Autores principales: Rampogu, Shailima, Baek, Ayoung, Son, Minky, Park, Chanin, Yoon, Sanghwa, Parate, Shraddha, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003205/
https://www.ncbi.nlm.nih.gov/pubmed/32039312
http://dx.doi.org/10.1021/acsomega.9b02263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003205/
https://www.ncbi.nlm.nih.gov/pubmed/32039312
http://dx.doi.org/10.1021/acsomega.9b02263

Ejemplares similares