miR-142-5p as a CXCR4-Targeted MicroRNA Attenuates SDF-1-Induced Chondrocyte Apoptosis and Cartilage Degradation via Inactivating MAPK Signaling Pathway

Osteoarthritis (OA) is a chronic joint function disorder with characteristics of chondrocytes reduction and extracellular matrix (ECM) components destruction. MicroRNAs (miRNAs) and the SDF-1/CXCR4 axis are essential factors of chondrocyte apoptosis and ECM degeneration. However, very few studies ha...

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Detalles Bibliográficos
Autores principales: Xiang, Yaoyv, Li, Yanlin, Yang, Lingjian, He, Yinghong, Jia, Di, Hu, Xidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003277/
https://www.ncbi.nlm.nih.gov/pubmed/32047668
http://dx.doi.org/10.1155/2020/4508108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003277/
https://www.ncbi.nlm.nih.gov/pubmed/32047668
http://dx.doi.org/10.1155/2020/4508108

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