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miR-142-5p as a CXCR4-Targeted MicroRNA Attenuates SDF-1-Induced Chondrocyte Apoptosis and Cartilage Degradation via Inactivating MAPK Signaling Pathway

Osteoarthritis (OA) is a chronic joint function disorder with characteristics of chondrocytes reduction and extracellular matrix (ECM) components destruction. MicroRNAs (miRNAs) and the SDF-1/CXCR4 axis are essential factors of chondrocyte apoptosis and ECM degeneration. However, very few studies ha...

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Detalles Bibliográficos
Autores principales:	Xiang, Yaoyv, Li, Yanlin, Yang, Lingjian, He, Yinghong, Jia, Di, Hu, Xidan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003277/ https://www.ncbi.nlm.nih.gov/pubmed/32047668 http://dx.doi.org/10.1155/2020/4508108

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