CD73 sustained cancer-stem-cell traits by promoting SOX9 expression and stability in hepatocellular carcinoma

BACKGROUND: Aberrant AKT activation contributes to cancer stem cell (CSC) traits in hepatocellular carcinoma (HCC). We previously reported that CD73 activated AKT signaling via the Rap1/P110β cascade. Here, we further explored the roles of CD73 in regulating CSC characteristics of HCC. METHODS: CD73...

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Detalles Bibliográficos
Autores principales: Ma, Xiao-Lu, Hu, Bo, Tang, Wei-Guo, Xie, Su-Hong, Ren, Ning, Guo, Lin, Lu, Ren-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003355/
https://www.ncbi.nlm.nih.gov/pubmed/32024555
http://dx.doi.org/10.1186/s13045-020-0845-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003355/
https://www.ncbi.nlm.nih.gov/pubmed/32024555
http://dx.doi.org/10.1186/s13045-020-0845-z

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