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Efficacy of platinum-based chemotherapy and prognosis of patients with pancreatic cancer with homologous recombination deficiency: comparative analysis of published clinical studies

The aim of our study was to determine the effect of homologous recombination deficiency (HRD) on prognosis and efficacy of platinum-based chemotherapy in patients with pancreatic cancer (PC). We performed PubMed and Embase database queries. We included 4 studies into the meta-analysis and 16 studies...

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Detalles Bibliográficos
Autores principales: Pokataev, Ilya, Fedyanin, Mikhail, Polyanskaya, Elizaveta, Popova, Anna, Agafonova, Julia, Menshikova, Sophia, Tryakin, Alexey, Rumyantsev, Alexey, Tjulandin, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003386/
https://www.ncbi.nlm.nih.gov/pubmed/33551067
http://dx.doi.org/10.1136/esmoopen-2019-000578