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MiR-140 targets RAP2A to enable the proliferation of insulin-treated ovarian granulosa cells

BACKGROUND: We elucidated the role of specific MicroRNAs (miRNAs) in the development of polycystic ovary syndrome (PCOS) and explained the changes in the proliferation of granulosa cells. Excised ovarian cortex specimens were collected for miRNA profiling analysis (n = 20 PCOS females and 5 non-PCOS...

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Detalles Bibliográficos
Autores principales: Xiong, Zhengfang, Li, Bing, Wang, Wenjuan, Zeng, Xianghui, Li, Binye, Jian, Shengyan, Wang, Liyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003402/
https://www.ncbi.nlm.nih.gov/pubmed/32024547
http://dx.doi.org/10.1186/s13048-020-0611-4