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Intervertebral disc degeneration in mice with type II diabetes induced by leptin receptor deficiency
BACKGROUND: The leptin receptor-deficient knockout (db/db) mouse is a well-established model for studying type II diabetes mellitus (T2DM). T2DM is an important risk factor of intervertebral disc degeneration (IVDD). Although the relationship between type I diabetes and IVDD has been reported by man...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003448/ https://www.ncbi.nlm.nih.gov/pubmed/32024487 http://dx.doi.org/10.1186/s12891-020-3091-1 |