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Microscopic visualization of virus removal by dedicated filters used in biopharmaceutical processing: Impact of membrane structure and localization of captured virus particles

Virus filtration with nanometer size exclusion membranes (“nanofiltration”) is effective for removing infectious agents from biopharmaceuticals. While the virus removal capability of virus removal filters is typically evaluated based on calculation of logarithmic reduction value (LRV) of virus infec...

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Detalles Bibliográficos
Autores principales: Adan‐Kubo, Jun, Tsujikawa, Muneo, Takahashi, Kadue, Hongo‐Hirasaki, Tomoko, Sakai, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003479/
https://www.ncbi.nlm.nih.gov/pubmed/31228338
http://dx.doi.org/10.1002/btpr.2875