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Integrative prediction of gene expression with chromatin accessibility and conformation data

BACKGROUND: Enhancers play a fundamental role in orchestrating cell state and development. Although several methods have been developed to identify enhancers, linking them to their target genes is still an open problem. Several theories have been proposed on the functional mechanisms of enhancers, w...

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Detalles Bibliográficos
Autores principales: Schmidt, Florian, Kern, Fabian, Schulz, Marcel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003490/
https://www.ncbi.nlm.nih.gov/pubmed/32029002
http://dx.doi.org/10.1186/s13072-020-0327-0