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Pharmacological inhibition of STAT3 pathway ameliorates acute liver injury in vivo via inactivation of inflammatory macrophages and hepatic stellate cells

Liver diseases represent a major health problem worldwide, in particular, acute liver injury is associated with high mortality and morbidity. Inflammatory macrophages and hepatic stellate cells (HSCs) are known to be involved in the pathogenesis of acute liver injury. In this study, we have investig...

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Detalles Bibliográficos
Autores principales: Öztürk Akcora, Büsra, Vassilios Gabriël, Alexandros, Ortiz‐Perez, Ana, Bansal, Ruchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003653/
https://www.ncbi.nlm.nih.gov/pubmed/32123858
http://dx.doi.org/10.1096/fba.2019-00070