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Tumor necrosis factor receptor‐2 signaling pathways promote survival of cancer stem‐like CD133(+) cells in clear cell renal carcinoma

Clear cell renal cell carcinoma (ccRCC) contains cancer stem‐like cells (CSCs) that express CD133 (ccRCC‐CD133(+)). CSCs are rarely in cell cycle and, as nonproliferating cells, resist most chemotherapeutic agents. Previously, we reported that tumor necrosis factor receptor‐2 (TNFR2) signaling promo...

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Detalles Bibliográficos
Autores principales: Bradley, John R., Wang, Jun, Pacey, Simon, Warren, Anne Y., Pober, Jordan S., Al‐Lamki, Rafia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003657/
https://www.ncbi.nlm.nih.gov/pubmed/32123862
http://dx.doi.org/10.1096/fba.2019-00071