Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells

BACKGROUND: Epithelial-mesenchymal transition (EMT) plays an important role in fibrosis, chronic inflammation, tumor metastasis, etc. Glycyrrhizin, an active component extracted from licorice plant, has been reported to treat a variety of inflammatory reactions through inhibiting high-mobility group...

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Detalles Bibliográficos
Autores principales: Gui, Yanni, Sun, Jian, You, Wenjie, Wei, Yuanhui, Tian, Han, Jiang, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003690/
https://www.ncbi.nlm.nih.gov/pubmed/32117622
http://dx.doi.org/10.7717/peerj.8514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003690/
https://www.ncbi.nlm.nih.gov/pubmed/32117622
http://dx.doi.org/10.7717/peerj.8514

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