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Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells
BACKGROUND: Epithelial-mesenchymal transition (EMT) plays an important role in fibrosis, chronic inflammation, tumor metastasis, etc. Glycyrrhizin, an active component extracted from licorice plant, has been reported to treat a variety of inflammatory reactions through inhibiting high-mobility group...
Autores principales: | Gui, Yanni, Sun, Jian, You, Wenjie, Wei, Yuanhui, Tian, Han, Jiang, Shujuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003690/ https://www.ncbi.nlm.nih.gov/pubmed/32117622 http://dx.doi.org/10.7717/peerj.8514 |
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