Phase 1 Dose‐Escalation Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Tofacitinib in Japanese Healthy Volunteers

The aim of the study was to characterize the pharmacokinetics, safety, and tolerability of tofacitinib, an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis in healthy Japanese volunteers, and to compare these outcomes with those of he...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyoshi, So, Krishnaswami, Sriram, Toyoizumi, Shigeyuki, Nakamura, Hiroyuki, Zwillich, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003739/
https://www.ncbi.nlm.nih.gov/pubmed/31713350
http://dx.doi.org/10.1002/cpdd.741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003739/
https://www.ncbi.nlm.nih.gov/pubmed/31713350
http://dx.doi.org/10.1002/cpdd.741

Ejemplares similares