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Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes

Viruses can inhibit host autophagy through multiple mechanisms, and evasion of autophagy plays an important role in immune suppression and viral oncogenesis. Merkel cell polyomavirus (MCPyV) T‐antigens are expressed and involved in the pathogenesis of a large proportion of Merkel cell carcinoma (MCC...

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Detalles Bibliográficos
Autores principales: Kumar, Satendra, Xie, Hong, Shi, Hao, Gao, Jiwei, Juhlin, Carl Christofer, Björnhagen, Viveca, Höög, Anders, Lee, Linkiat, Larsson, Catharina, Lui, Weng‐Onn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003823/
https://www.ncbi.nlm.nih.gov/pubmed/31180579
http://dx.doi.org/10.1002/ijc.32503