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Saturated oxygen and nitrogen heterocycles via oxidative coupling of alkyltrifluoroborates with alkenols, alkenoic acids and protected alkenylamines

Saturated heterocycles are important components of many bioactive compounds. The method disclosed herein enables a general route to a range of 5-, 6- and 7-membered oxygen and nitrogen heterocycles by coupling potassium alkyltrifluoroborates with heteroatom-tethered alkenes, predominantly styrenes,...

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Detalles Bibliográficos
Autores principales: Shikora, Jonathan M., Um, Chanchamnan, Khoder, Zainab M., Chemler, Sherry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003886/
https://www.ncbi.nlm.nih.gov/pubmed/32055311
http://dx.doi.org/10.1039/c9sc02835h