Cargando…

Thermodynamic and Structural Behavior of α‐Galactosylceramide and C6‐Functionalized α‐GalCer in 2D Layers at the Air–Liquid Interface

α‐Galactosylceramide (α‐GalCer; KRN7000) is a ligand for the glycoprotein CD1d that presents lipid antigens to natural killer T cells. Therefore, KRN7000 as well as some modified versions thereof have been widely investigated as part of novel immunotherapies. To examine the impact of structural modi...

Descripción completa

Detalles Bibliográficos
Autores principales: Brezesinski, Gerald, Calow, Adam D. J., Pereira, Claney L., Seeberger, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004034/
https://www.ncbi.nlm.nih.gov/pubmed/31544285
http://dx.doi.org/10.1002/cbic.201900491