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Phase 2 study of efgartigimod, a novel FcRn antagonist, in adult patients with primary immune thrombocytopenia

Primary immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder, characterized by a low platelet count (<100 × 10(9)/L) in the absence of other causes associated with thrombocytopenia. In most patients, IgG autoantibodies directed against platelet receptors can be detected. They...

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Detalles Bibliográficos
Autores principales: Newland, Adrian C., Sánchez‐González, Blanca, Rejtő, László, Egyed, Miklos, Romanyuk, Nataliya, Godar, Marie, Verschueren, Katrien, Gandini, Domenica, Ulrichts, Peter, Beauchamp, Jon, Dreier, Torsten, Ward, E. Sally, Michel, Marc, Liebman, Howard A., de Haard, Hans, Leupin, Nicolas, Kuter, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004056/
https://www.ncbi.nlm.nih.gov/pubmed/31821591
http://dx.doi.org/10.1002/ajh.25680