Hyperglycemia aggravates acute liver injury by promoting liver‐resident macrophage NLRP3 inflammasome activation via the inhibition of AMPK/mTOR‐mediated autophagy induction

Although the detrimental effects of diabetes mellitus/hyperglycemia have been observed in many liver disease models, the function and mechanism of hyperglycemia regulating liver‐resident macrophages, Kupffer cells (KCs), in thioacetamide (TAA)‐induced liver injury remain largely unknown. In this stu...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Wei, Song, Zhou, Shun, Qiu, Jiannan, Shi, Chenyu, Liu, Rui, Zhou, Haoming, Lu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004066/
https://www.ncbi.nlm.nih.gov/pubmed/31625631
http://dx.doi.org/10.1111/imcb.12297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004066/
https://www.ncbi.nlm.nih.gov/pubmed/31625631
http://dx.doi.org/10.1111/imcb.12297

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