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Intracranial antitumor activity with encorafenib plus binimetinib in patients with melanoma brain metastases: A case series
BACKGROUND: Sixty percent of patients with stage IV melanoma may develop brain metastases, which result in significantly increased morbidity and a poor overall prognosis. Phase 3 studies of melanoma usually exclude patients with untreated brain metastases; therefore, clinical data for intracranial r...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004095/ https://www.ncbi.nlm.nih.gov/pubmed/31658370 http://dx.doi.org/10.1002/cncr.32547 |