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The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer

Currently, no effective targeted therapeutics exists for treatment of metastatic prostate cancer (PCa). Given that matrix metalloproteinases 9 (MMP9) and its associated vascular endothelial growth factor (VEGF) are critical for tumor vascularization and invasion under castration‐resistant condition,...

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Detalles Bibliográficos
Autores principales: Larsson, Per, Syed Khaja, Azharuddin Sajid, Semenas, Julius, Wang, Tianyan, Sarwar, Martuza, Dizeyi, Nishtman, Simoulis, Athanasios, Hedblom, Andreas, Wai, Sun Nyunt, Ødum, Niels, Persson, Jenny L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004098/
https://www.ncbi.nlm.nih.gov/pubmed/31381135
http://dx.doi.org/10.1002/ijc.32607