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The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer
Currently, no effective targeted therapeutics exists for treatment of metastatic prostate cancer (PCa). Given that matrix metalloproteinases 9 (MMP9) and its associated vascular endothelial growth factor (VEGF) are critical for tumor vascularization and invasion under castration‐resistant condition,...
Autores principales: | Larsson, Per, Syed Khaja, Azharuddin Sajid, Semenas, Julius, Wang, Tianyan, Sarwar, Martuza, Dizeyi, Nishtman, Simoulis, Athanasios, Hedblom, Andreas, Wai, Sun Nyunt, Ødum, Niels, Persson, Jenny L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004098/ https://www.ncbi.nlm.nih.gov/pubmed/31381135 http://dx.doi.org/10.1002/ijc.32607 |
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