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Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD)

Smoke exposure is known to decrease total pulmonary surfactant and alter its composition, but the role of surfactant in chronic obstructive pulmonary disease (COPD) remains unknown. We aimed to analyze the compositional changes in the surfactant lipidome in COPD and identify specific lipids associat...

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Detalles Bibliográficos
Autores principales: Agudelo, Christina W., Kumley, Britta K., Area-Gomez, Estela, Xu, Yimeng, Dabo, Abdoulaye J., Geraghty, Patrick, Campos, Michael, Foronjy, Robert, Garcia-Arcos, Itsaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004328/
https://www.ncbi.nlm.nih.gov/pubmed/32027677
http://dx.doi.org/10.1371/journal.pone.0228279