Discovery, expression, cellular localization, and molecular properties of a novel, alternative spliced HP1γ isoform, lacking the chromoshadow domain

By reading the H3K9Me3 mark through their N-terminal chromodomain (CD), HP1 proteins play a significant role in cancer-associated processes, including cell proliferation, differentiation, chromosomal stability, and DNA repair. Here, we used a combination of bioinformatics-based methodologies, as wel...

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Detalles Bibliográficos
Autores principales: Mathison, Angela, Milech De Assuncao, Thiago, Dsouza, Nikita R., Williams, Monique, Zimmermann, Michael T., Urrutia, Raul, Lomberk, Gwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004349/
https://www.ncbi.nlm.nih.gov/pubmed/32027651
http://dx.doi.org/10.1371/journal.pone.0217452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004349/
https://www.ncbi.nlm.nih.gov/pubmed/32027651
http://dx.doi.org/10.1371/journal.pone.0217452

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