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Probing remote residues important for catalysis in Escherichia coli ornithine transcarbamoylase
Understanding how enzymes achieve their tremendous catalytic power is a major question in biochemistry. Greater understanding is also needed for enzyme engineering applications. In many cases, enzyme efficiency and specificity depend on residues not in direct contact with the substrate, termed remot...
Autores principales: | Ngu, Lisa, Winters, Jenifer N., Nguyen, Kien, Ramos, Kevin E., DeLateur, Nicholas A., Makowski, Lee, Whitford, Paul C., Ondrechen, Mary Jo, Beuning, Penny J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004355/ https://www.ncbi.nlm.nih.gov/pubmed/32027716 http://dx.doi.org/10.1371/journal.pone.0228487 |
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