Informatics investigations into anti-thyroid drug induced agranulocytosis associated with multiple HLA-B alleles

INTRODUCTION: Adverse drug reactions have been linked with HLA alleles in different studies. These HLA proteins play an essential role in the adaptive immune response for the presentation of self and non-self peptides. Anti-thyroid drugs methimazole and propylthiouracil have been associated with dru...

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Detalles Bibliográficos
Autores principales: Ramsbottom, Kerry A., Carr, Daniel F., Rigden, Daniel J., Jones, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004376/
https://www.ncbi.nlm.nih.gov/pubmed/32027661
http://dx.doi.org/10.1371/journal.pone.0220754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004376/
https://www.ncbi.nlm.nih.gov/pubmed/32027661
http://dx.doi.org/10.1371/journal.pone.0220754

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