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Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly

Retrovirus assembly is driven by the multidomain structural protein Gag. Interactions between the capsid domains (CA) of Gag result in Gag multimerization, leading to an immature virus particle that is formed by a protein lattice based on dimeric, trimeric, and hexameric protein contacts. Among retr...

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Detalles Bibliográficos
Autores principales: Dick, Robert A., Xu, Chaoyi, Morado, Dustin R., Kravchuk, Vladyslav, Ricana, Clifton L., Lyddon, Terri D., Broad, Arianna M., Feathers, J. Ryan, Johnson, Marc C., Vogt, Volker M., Perilla, Juan R., Briggs, John A. G., Schur, Florian K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004409/
https://www.ncbi.nlm.nih.gov/pubmed/31986188
http://dx.doi.org/10.1371/journal.ppat.1008277