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Exposing Toxoplasma gondii hiding inside the vacuole: a role for GBPs, autophagy and host cell death
The intracellular parasite Toxoplasma gondii resides inside a vacuole, which shields it from the host’s intracellular defense mechanisms. The cytokine interferon gamma (IFNγ) upregulates host cell effector pathways that are able to destroy the vacuole, restrict parasite growth and induce host cell d...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004510/ https://www.ncbi.nlm.nih.gov/pubmed/29141239 http://dx.doi.org/10.1016/j.mib.2017.10.021 |