FLT3 mutations in acute myeloid leukemia: Therapeutic paradigm beyond inhibitor development

FMS‐like tyrosine kinase 3 (FLT3) is a type III receptor tyrosine kinase that plays an important role in hematopoietic cell survival, proliferation and differentiation. The most clinically important point is that mutation of the FLT3 gene is the most frequent genetic alteration and a poor prognostic...

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Detalles Bibliográficos
Autores principales: Kiyoi, Hitoshi, Kawashima, Naomi, Ishikawa, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004512/
https://www.ncbi.nlm.nih.gov/pubmed/31821677
http://dx.doi.org/10.1111/cas.14274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004512/
https://www.ncbi.nlm.nih.gov/pubmed/31821677
http://dx.doi.org/10.1111/cas.14274

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