Cargando…

Cellular senescence and senescence‐associated secretory phenotype via the cGAS‐STING signaling pathway in cancer

Cellular senescence is historically regarded as a tumor suppression mechanism to prevent damaged cells from aberrant proliferation in benign and premalignant tumors. However, recent findings have suggested that senescent cells contribute to tumorigenesis and age‐associated pathologies through the se...

Descripción completa

Detalles Bibliográficos
Autores principales: Loo, Tze Mun, Miyata, Kenichi, Tanaka, Yoko, Takahashi, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004529/
https://www.ncbi.nlm.nih.gov/pubmed/31799772
http://dx.doi.org/10.1111/cas.14266