Identification and characterization of the binding sequences and target genes of p53 lacking the 1st transactivation domain

The tumor suppressor gene p53 encodes a transcriptional activator that has two transactivation domains (TAD) located in its amino terminus. These two TAD can transactivate genes independently, and at least one TAD is required for p53 transactivation function. The 1st TAD (a.a. 1‐40) is essential for...

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Detalles Bibliográficos
Autores principales: Suzuki, Shiori, Tsutsumi, Shuichi, Chen, Yu, Ozeki, Chikako, Okabe, Atsushi, Kawase, Tatsuya, Aburatani, Hiroyuki, Ohki, Rieko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004532/
https://www.ncbi.nlm.nih.gov/pubmed/31834974
http://dx.doi.org/10.1111/cas.14279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004532/
https://www.ncbi.nlm.nih.gov/pubmed/31834974
http://dx.doi.org/10.1111/cas.14279

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