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Gene regulatory network reconstruction using single-cell RNA sequencing of barcoded genotypes in diverse environments

Understanding how gene expression programs are controlled requires identifying regulatory relationships between transcription factors and target genes. Gene regulatory networks are typically constructed from gene expression data acquired following genetic perturbation or environmental stimulus. Sing...

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Detalles Bibliográficos
Autores principales: Jackson, Christopher A, Castro, Dayanne M, Saldi, Giuseppe-Antonio, Bonneau, Richard, Gresham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004572/
https://www.ncbi.nlm.nih.gov/pubmed/31985403
http://dx.doi.org/10.7554/eLife.51254