Muscle weakness and impaired motor coordination in hyperpolarization-activated cyclic nucleotide-gated potassium channel 1-deficient rats

Hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 (HCN1) contribute to spontaneous rhythmic activity in different tissues, including the heart and brain. Deficiency in HCN1 function is associated with sick sinus syndrome in mice and epilepsy in humans. We recently developed Hcn...

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Detalles Bibliográficos
Autores principales: Nishitani, Ai, Yoshihara, Toru, Tanaka, Miyuu, Kuwamura, Mitsuru, Asano, Masahide, Tsubota, Yuji, Kuramoto, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2019
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004805/
https://www.ncbi.nlm.nih.gov/pubmed/31292305
http://dx.doi.org/10.1538/expanim.19-0067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004805/
https://www.ncbi.nlm.nih.gov/pubmed/31292305
http://dx.doi.org/10.1538/expanim.19-0067

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