Ten-eleven translocation-2 affects the fate of cells and has therapeutic potential in digestive tumors

Ten-eleven translocation (TET) methylcytosine dioxygenases catalyze the oxidative reactions of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC), and 5-carboxylcytosine (5-caC), which are intermediate steps during DNA demethylation. It is reported that somatic mutat...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Zhang, Jing, Qi, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Medical Association 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004935/
https://www.ncbi.nlm.nih.gov/pubmed/32055786
http://dx.doi.org/10.1016/j.cdtm.2019.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004935/
https://www.ncbi.nlm.nih.gov/pubmed/32055786
http://dx.doi.org/10.1016/j.cdtm.2019.12.001

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