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Insertions and Duplications in the Polyproline Region of the Hepatitis E Virus

Recombinant strains of hepatitis E virus (HEV) with insertions of human genomic fragments or HEV sequence duplications in the sequence encoding the polyproline region (PPR) were previously described in chronically infected patients. Such genomic rearrangements confer a replicative advantage in vitro...

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Detalles Bibliográficos
Autores principales: Lhomme, Sébastien, Nicot, Florence, Jeanne, Nicolas, Dimeglio, Chloé, Roulet, Alain, Lefebvre, Caroline, Carcenac, Romain, Manno, Maxime, Dubois, Martine, Peron, Jean-Marie, Alric, Laurent, Kamar, Nassim, Abravanel, Florence, Izopet, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004952/
https://www.ncbi.nlm.nih.gov/pubmed/32082274
http://dx.doi.org/10.3389/fmicb.2020.00001