Loss of miR-369 Promotes Tau Phosphorylation by Targeting the Fyn and Serine/Threonine-Protein Kinase 2 Signaling Pathways in Alzheimer’s Disease Mice

INTRODUCTION: Alzheimer’s disease (AD) is a progressive neurodegenerative dementia with the key pathological hallmarks amyloid-beta deposition and neurofibrillary tangles composed of hyperphosphorylated tau. microRNAs (miRNAs) are small non-coding RNAs that contribute to the pathogenesis of AD. In t...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Xiaoguang, Xian, Xiaohui, Fang, Mingxing, Fan, Shujuan, Li, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004974/
https://www.ncbi.nlm.nih.gov/pubmed/32082134
http://dx.doi.org/10.3389/fnagi.2019.00365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004974/
https://www.ncbi.nlm.nih.gov/pubmed/32082134
http://dx.doi.org/10.3389/fnagi.2019.00365

Ejemplares similares