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Loss of miR-369 Promotes Tau Phosphorylation by Targeting the Fyn and Serine/Threonine-Protein Kinase 2 Signaling Pathways in Alzheimer’s Disease Mice

INTRODUCTION: Alzheimer’s disease (AD) is a progressive neurodegenerative dementia with the key pathological hallmarks amyloid-beta deposition and neurofibrillary tangles composed of hyperphosphorylated tau. microRNAs (miRNAs) are small non-coding RNAs that contribute to the pathogenesis of AD. In t...

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Detalles Bibliográficos
Autores principales:	Yao, Xiaoguang, Xian, Xiaohui, Fang, Mingxing, Fan, Shujuan, Li, Wenbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004974/ https://www.ncbi.nlm.nih.gov/pubmed/32082134 http://dx.doi.org/10.3389/fnagi.2019.00365

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