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Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

The glymphatic system (GS) hypothesis states that advective driven cerebrospinal fluid (CSF) influx from the perivascular spaces into the interstitial fluid space rapidly transport solutes and clear waste from brain. However, the presence of advection in neuropil is contested and solutes are claimed...

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Detalles Bibliográficos
Autores principales: Kounda, Sunil, Elkin, Rena, Nadeem, Saad, Xue, Yuechuan, Constantinou, Stefan, Sanggaard, Simon, Liu, Xiaodan, Monte, Brittany, Xu, Feng, Van Nostrand, William, Nedergaard, Maiken, Lee, Hedok, Wardlaw, Joanna, Benveniste, Helene, Tannenbaum, Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004986/
https://www.ncbi.nlm.nih.gov/pubmed/32029859
http://dx.doi.org/10.1038/s41598-020-59045-9