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Developing a xenograft model of human vasculature in the mouse ear pinna

Humanised xenograft models allow for the analysis of human tissue within a physiological environment in vivo. However, current models often rely on the angiogenesis and ingrowth of recipient vasculature to perfuse tissues, preventing analysis of biological processes and diseases involving human bloo...

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Detalles Bibliográficos
Autores principales: Meehan, Gavin R., Scales, Hannah E., Osii, Rowland, De Niz, Mariana, Lawton, Jennifer C., Marti, Matthias, Garside, Paul, Craig, Alister, Brewer, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004987/
https://www.ncbi.nlm.nih.gov/pubmed/32029768
http://dx.doi.org/10.1038/s41598-020-58650-y